A Multi-Omics Study Reveals Pathway-Level Insights and Predictive Biomarkers in pediatric TB
These findings demonstrate the advantage of combining complementary molecular layers to gain a deeper understanding of disease mechanisms and highlight the potential of proteomics for improving pediatric TB diagnosis.
Authors
- Aarti Kinikar (ORCID: https://orcid.org/0000-0001-9466-1130)
- Gunilla Källenius (ORCID: https://orcid.org/0000-0002-8921-0551)
- Esin Nkereuwem
- Zaynab Mousavian (ORCID: https://orcid.org/0009-0003-3489-126X)
- Christopher Sundling (ORCID: https://orcid.org/0000-0002-6138-690X)
- Juaneta Luiz (ORCID: https://orcid.org/0009-0005-7921-8129)
- Peter Wambi (ORCID: https://orcid.org/0000-0002-9195-0778)
- Mandar Paradkar (ORCID: https://orcid.org/0000-0001-9843-4656)
- Danielle L. Swaney (ORCID: https://orcid.org/0000-0001-6119-6084)
- Eric Wobudeya (ORCID: https://orcid.org/0000-0001-9574-5539)
- Roger Calderon
- Beate Kampmann
- Mark R. Segal
- George B. Sigal
- Devan Jaganath
- Adithya Cattamanchi
- Jeffrey M. Collins
- Joel D. Ernst
- Heather J. Zar
- Molly F. Franke
Institutions
- South African Medical Research Council (ZA)
- Government Medical College (IN)
- Gladstone Institutes (US)
- Karolinska University Hospital (SE)
- Harvard University (US)
- Johns Hopkins University (US)
- Emory University (US)
- University of California, San Francisco (US)
- B. J. Medical College & Sassoon Hospital (IN)
- University of California, Irvine (US)
- Dora Nginza Hospital (ZA)
- Karolinska Institutet (SE)
- Malaria Consortium (UG)
- Quantitative BioSciences (US)
- MRC Unit the Gambia (GM)
- Global Brain Health Institute (US)
- Meso Scale Discovery (United States) (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- medRxiv
- Published
- 2026-03-16
- DOI
- https://doi.org/10.64898/2026.03.13.26348257
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- UK Research and Innovation
- South African Medical Research Council
- Vetenskapsrådet
- Erik och Edith Fernströms Stiftelse för Medicinsk Forskning
- National Institutes of Health
- University of California, San Francisco
- Medical Research Council
- National Institute of Allergy and Infectious Diseases