Cerebrovascular CTA radiomics for objective collateral grading in acute ischemic stroke
Collateral circulation status informs prognosis and guides treatment in acute stroke, but grading is rater-dependent; our pipeline standardizes collateral assessment. We propose a CTA radiomics approach, trained and validated on multicenter data, externally tested on an independent cohort, demonstrating high effectiveness and generalizability. Automated and reliable collateral scoring has the potential to reduce inter-rater variability, improve workflow efficiency, and support individualized treatment decisions.
Authors
- Peter Vajkoczy (ORCID: https://orcid.org/0000-0003-4350-392X)
- Adam Hilbert (ORCID: https://orcid.org/0000-0003-3447-5453)
- Orhun Utku Aydin (ORCID: https://orcid.org/0000-0002-8808-7651)
- Dietmar Frey (ORCID: https://orcid.org/0000-0001-5407-2331)
- Dimitrios Rallios
- Susanne Bonekamp
- Aad van der Lugt
- Martin Bendszus
- Wim Van H. van Zwam
- Charles Majoie
Institutions
- Heidelberg University (DE)
- Maastricht University Medical Centre (NL)
- Erasmus MC (NL)
- University Hospital Heidelberg (DE)
- Amsterdam University Medical Centers (NL)
- Charité - Universitätsmedizin Berlin (DE)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1186/s41747-026-00680-8
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- HORIZON EUROPE Framework Programme