A comparative study of dextran sodium sulfate-induced and spleen-kidney syndrome-based ulcerative colitis models

While both models reflect inflammation and immune dysregulation, the SKYD-UC model better simulates the refractory nature of UC, offering an effective animal model for UC research.

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Publication Details

Journal
Biochemistry and Biophysics Reports
Published
2026-03-16
DOI
https://doi.org/10.1016/j.bbrep.2026.102524
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

A comparative study of dextran sodium sulfate-induced and spleen-kidney syndrome-based ulcerative colitis models

Xia Lin, You Huang, Chaomei Fu, Zhishu Tang et al.
Biochemistry and Biophysics Reports
Inflammatory Bowel Disease
article

A comparative study of dextran sodium sulfate-induced and spleen-kidney syndrome-based ulcerative colitis models

Xia Lin, You Huang, Chaomei Fu, Zhishu Tang, Yue Zhang, Zhen Zhang, Yiwen Hao, Shasha Yang, Fuyu Xie, Hang Zhou, Xing Zhang, Yue Wang
article en

Abstract

While both models reflect inflammation and immune dysregulation, the SKYD-UC model better simulates the refractory nature of UC, offering an effective animal model for UC research.

Biochemistry and Biophysics ReportsVol. 46
Beijing University of Chinese Medicine (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), China Academy of Chinese Medical Sciences (CN), Southwest Jiaotong University (CN), Chengdu University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 21%
Inflammatory Bowel Disease
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A comparative study of dextran sodium sulfate-induced and spleen-kidney syndrome-based ulcerative colitis models — Xia Lin, You Huang, et al. · Biochemistry and Biophysics Reports (2026) | TGRS Research Map | TGRS