A comparative study of dextran sodium sulfate-induced and spleen-kidney syndrome-based ulcerative colitis models
While both models reflect inflammation and immune dysregulation, the SKYD-UC model better simulates the refractory nature of UC, offering an effective animal model for UC research.
Authors
- Xia Lin (ORCID: https://orcid.org/0000-0001-6446-542X)
- You Huang
- Chaomei Fu
- Zhishu Tang
- Yue Zhang
- Zhen Zhang
- Yiwen Hao
- Shasha Yang
- Fuyu Xie
- Hang Zhou
- Xing Zhang
- Yue Wang
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China Academy of Chinese Medical Sciences (CN)
- Southwest Jiaotong University (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2026-03-16
- DOI
- https://doi.org/10.1016/j.bbrep.2026.102524
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00