Intraindividual development of MR lung perfusion parameters in children after congenital diaphragmatic hernia at 2 and 10 years
Question Lung perfusion development in children with CDH between ages 2 and 10, including prenatal and postnatal influencing factors. Findings Ipsilateral lung perfusion remained reduced, PBV decreased, and low prenatal o/e FLV correlated with persistently impaired perfusion. Clinical relevance Children with severe prenatal lung hypoplasia show lasting perfusion deficits into adolescence. Early risk assessment enables timely, targeted interventions to mitigate long-term pulmonary impairment.
Authors
- Christel Weiß (ORCID: https://orcid.org/0000-0002-8692-5690)
- Julia Elrod (ORCID: https://orcid.org/0000-0001-8479-2305)
- Meike Weis (ORCID: https://orcid.org/0000-0002-8085-6612)
- Greta Thater (ORCID: https://orcid.org/0000-0001-6377-0473)
- Schanas Jawhar
- S O Schoenberg
- Michael Boettcher
- Angelika Enns-Ercan
- Thomas Schaible
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Medical Centre Mannheim (DE)
Publication Details
- Journal
- European Radiology
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1007/s00330-026-12443-5
- Primary Topic
- Congenital Diaphragmatic Hernia Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft