Long-Term follow-up of S0221, comparing alternative Dose-Schedules of anthracycline/taxane therapy in early breast cancer

As there were no significant outcome differences in DFS or OS between the studied schedules of AC and P with extended follow-up in the original or revised protocol, either paclitaxel schedule may be recommended, with selection based on toxicity, cost, or patient preference.

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Publication Details

Journal
JNCI Cancer Spectrum
Published
2026-03-12
DOI
https://doi.org/10.1093/jncics/pkag024
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Long-Term follow-up of S0221, comparing alternative Dose-Schedules of anthracycline/taxane therapy in early breast cancer

Azka Ali, Danika L. Lew, Julie R. Gralow, Lawrence E. Flaherty et al.
JNCI Cancer Spectrum
Breast Cancer Treatment Studies
article

Long-Term follow-up of S0221, comparing alternative Dose-Schedules of anthracycline/taxane therapy in early breast cancer

Azka Ali, Danika L. Lew, Julie R. Gralow, Lawrence E. Flaherty, Kathy S. Albain, Bradley A. McGregor, Gordan Srkalović, William E. Barlow, Muhammad Salim, G. Burton, Helen K. Chew, T. Hobday, Lajos Pusztai, George T Budd, Claudine Isaacs, Halle C F Moore, Gabriel N Hortobagyi, Priyanka Sharma
article en

Abstract

As there were no significant outcome differences in DFS or OS between the studied schedules of AC and P with extended follow-up in the original or revised protocol, either paclitaxel schedule may be recommended, with selection based on toxicity, cost, or patient preference.

JNCI Cancer Spectrum
Sparrow Health System (US), American Society of Clinical Oncology (US), Cleveland Clinic (US), The University of Texas MD Anderson Cancer Center (US), Loyola University Chicago (US), Georgetown University Medical Center (US), Yale Cancer Center (US), The Barbara Ann Karmanos Cancer Institute (US), Saskatchewan Cancer Agency (CA), Dana-Farber Cancer Institute (US), Mayo Clinic in Arizona (US), University of Kansas Medical Center (US), Mayo Clinic in Florida (US), University of California Davis Medical Center (US), Louisiana State University Health Sciences Center Shreveport (US)
Good health and well-being
Openalex Percentile: Top 21%
Breast Cancer Treatment Studies
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