A parallel UNet integrating KAN and mamba for medical image segmentation

Medical image segmentation is fundamental for delineating lesion and organ boundaries in clinical workflows. While UNet-based models remain widely used, CNN-dominant designs are limited in modeling long-range context, and Transformer-based variants often introduce substantial computational overhead due to quadratic attention. To address this issue, we propose KMP-UNet, a parallel U-shaped framework that combines a Mamba-based state-space branch for linear-complexity contextual modeling and a Kolmogorov-Arnold Network (KAN) branch for nonlinear feature representation. We further introduce a task-oriented fusion block and a skip refinement module to better exploit hierarchical encoder-decoder features. KMP-UNet has a compact model size (about 1.0M parameters in our implementation). We evaluate the proposed method on four public datasets (ISIC2017, ISIC2018, CVC-ClinicDB, and BUSI) using standard segmentation metrics. On ISIC2018, KMP-UNet achieves 0.9038 DSC and 0.9600 accuracy under our protocol. Extensive comparisons and targeted ablations are conducted to analyze the contribution of each component.

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Publication Details

Journal
Scientific Reports
Published
2026-03-15
DOI
https://doi.org/10.1038/s41598-026-43127-1
Primary Topic
AI in cancer detection
Type
article
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article

A parallel UNet integrating KAN and mamba for medical image segmentation

Wenxu Shi, Liming Xu, Jiayi Liu, Bochuan Zheng et al.
Scientific Reports
AI in cancer detection
article

A parallel UNet integrating KAN and mamba for medical image segmentation

Wenxu Shi, Liming Xu, Jiayi Liu, Bochuan Zheng, Jiabao Wu
article en

Abstract

Medical image segmentation is fundamental for delineating lesion and organ boundaries in clinical workflows. While UNet-based models remain widely used, CNN-dominant designs are limited in modeling long-range context, and Transformer-based variants often introduce substantial computational overhead due to quadratic attention. To address this issue, we propose KMP-UNet, a parallel U-shaped framework that combines a Mamba-based state-space branch for linear-complexity contextual modeling and a Kolmogorov-Arnold Network (KAN) branch for nonlinear feature representation. We further introduce a task-oriented fusion block and a skip refinement module to better exploit hierarchical encoder-decoder features. KMP-UNet has a compact model size (about 1.0M parameters in our implementation). We evaluate the proposed method on four public datasets (ISIC2017, ISIC2018, CVC-ClinicDB, and BUSI) using standard segmentation metrics. On ISIC2018, KMP-UNet achieves 0.9038 DSC and 0.9600 accuracy under our protocol. Extensive comparisons and targeted ablations are conducted to analyze the contribution of each component.

Scientific Reports
Army Medical University (CN), China West Normal University (CN)
Partnerships for the goals
Openalex Percentile: Top 24%
AI in cancer detection
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