The antinuclear antibody HEp-2 indirect immunofluorescence harmonization and competency assessment program of the Society for Clinical Microbiologists of Türkiye: analysis of 7-year assessment results

The results revealed good performance for many competent-level nuclear and cytoplasmic patterns and satisfactory reflex test recommendations. Persistent challenges were recognized, however, for patterns AC-29, AC-5, AC-20, and AC-0. Competency self-assessment, combined with collective performance evaluation, may provide insight for the harmonization of HEp-2 IIF reporting and improvement of laboratory-clinician collaboration.

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Publication Details

Journal
Laboratory Medicine
Published
2026-02-09
DOI
https://doi.org/10.1093/labmed/lmag001
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
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article

The antinuclear antibody HEp-2 indirect immunofluorescence harmonization and competency assessment program of the Society for Clinical Microbiologists of Türkiye: analysis of 7-year assessment results

Nilgün Kaşifoğlu, Neval Yurttutan Uyar, Ekrem Yaşar, Burçin Şener et al.
Laboratory Medicine
Monoclonal and Polyclonal Antibodies Research
article

The antinuclear antibody HEp-2 indirect immunofluorescence harmonization and competency assessment program of the Society for Clinical Microbiologists of Türkiye: analysis of 7-year assessment results

Nilgün Kaşifoğlu, Neval Yurttutan Uyar, Ekrem Yaşar, Burçin Şener, Neşe KAKLIKKAYA, Tutku Taskinoglu
article en

Abstract

The results revealed good performance for many competent-level nuclear and cytoplasmic patterns and satisfactory reflex test recommendations. Persistent challenges were recognized, however, for patterns AC-29, AC-5, AC-20, and AC-0. Competency self-assessment, combined with collective performance evaluation, may provide insight for the harmonization of HEp-2 IIF reporting and improvement of laboratory-clinician collaboration.

Laboratory MedicineVol. 57(2)
Dicle University (TR), Karadeniz Technical University (TR), Diyarbakır Askeri Hastanesi (TR), Turkish Aerospace Industries (Turkey) (TR), Eskişehir Osmangazi University (TR), Hacettepe University (TR), Istanbul University (TR)
Openalex Percentile: Top 22%
Monoclonal and Polyclonal Antibodies Research
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