The Prognostic Significance of Radiographic Progression Without PSA Progression in Patients With Metastatic Hormone‐Sensitive Prostate Cancer Treated With First‐Line ARPI Therapy
RP alone progression occurred in approximately one-fifth of patients and was associated with significantly poorer survival despite excellent PSA responses, underscoring the limitation of PSA-based monitoring and supporting routine imaging for early detection of PSA-incongruent disease progression in mHSPC.
Authors
- Tomohisa Matsunaga (ORCID: https://orcid.org/0000-0001-5238-2598)
- Kiyoshi Takahara (ORCID: https://orcid.org/0000-0002-4766-2074)
- Shogo Yamazaki
- Yuki Yoshikawa (ORCID: https://orcid.org/0000-0001-8834-5051)
- Keita Nakamori (ORCID: https://orcid.org/0009-0008-5015-7694)
- Kyosuke Nishio
- TAKUYA TSUJINO
- Ko Nakamura
- Takeshi Tsutsumi (ORCID: https://orcid.org/0000-0002-6144-9464)
- Kazumasa Komura (ORCID: https://orcid.org/0000-0001-5082-3054)
- Tatsuo Fukushima (ORCID: https://orcid.org/0009-0002-2823-0628)
- Moritoshi Sakamoto (ORCID: https://orcid.org/0009-0000-2053-0058)
- Taizo Uchimoto (ORCID: https://orcid.org/0000-0002-5200-9053)
- Shingo Toyoda
- Saizo Fujimoto
- Wataru Fukuokaya
- Takafumi Yanagisawa
- Kazuki Nishimura
- Haruhito Azuma
- Kazutoshi Fujita
- Keiichiro Mori
- Takahiro Kimura
- Masanobu Saruta
- Takuya Matsuda
- Atsuhiko Yoshizawa
- Ryoichi Maenosono
- Fumihiko Urabe
- Teruo Inamoto
Institutions
- Jikei University School of Medicine (JP)
- Fujita Health University (JP)
- Kawasaki Medical School (JP)
- Hamamatsu University School of Medicine (JP)
- Kindai University Hospital (JP)
- Osaka University of Pharmaceutical Sciences (JP)
- Kindai University (JP)
Publication Details
- Journal
- The Prostate
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1002/pros.70157
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00