Effectiveness and Tolerability of Vortioxetine in Major Depressive Disorder: A Real-World Study in Switzerland

Patients who initiated vortioxetine for treating a major depressive episode experienced improvements in depressive symptoms and functioning. Vortioxetine was well tolerated. Underestimation of depressive episode severity by clinicians reinforces the importance of using rating scales in clinical practice.

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Publication Details

Journal
Clinical Drug Investigation
Published
2026-03-15
DOI
https://doi.org/10.1007/s40261-026-01537-z
Primary Topic
Treatment of Major Depression
Type
article
Field-Weighted Citation Impact
0.00

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article

Effectiveness and Tolerability of Vortioxetine in Major Depressive Disorder: A Real-World Study in Switzerland

Gregor Hasler, Axel Baumann, Barbara Hochstrasser, Alexandra Sousek et al.
Clinical Drug Investigation
Treatment of Major Depression
article

Effectiveness and Tolerability of Vortioxetine in Major Depressive Disorder: A Real-World Study in Switzerland

Gregor Hasler, Axel Baumann, Barbara Hochstrasser, Alexandra Sousek, Martin Kammerer
article en

Abstract

Patients who initiated vortioxetine for treating a major depressive episode experienced improvements in depressive symptoms and functioning. Vortioxetine was well tolerated. Underestimation of depressive episode severity by clinicians reinforces the importance of using rating scales in clinical practice.

Clinical Drug Investigation
University of Fribourg (CH), Privatklinik Meiringen (CH), Lundbeck (Germany) (DE), Klinik und Poliklinik für Psychiatrie und Psychotherapie (DE), Imperial College London (GB)
H. Lundbeck A/S
Reduced inequalities
Openalex Percentile: Top 21%
Treatment of Major Depression
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