Kidney tubule injury is associated with sodium avidity and diuretic responsiveness in acute heart failure

Kidney tubular injury, as assessed by urine KIM-1 and NAG, is associated with greater sodium avidity and higher KIM-1 is associated with impaired diuretic responsiveness in AHF.

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Publication Details

Journal
ESC Heart Failure
Published
2026-03-12
DOI
https://doi.org/10.1093/eschf/xvag079
Primary Topic
Acute Kidney Injury Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Kidney tubule injury is associated with sodium avidity and diuretic responsiveness in acute heart failure

N. Wettersten, Yoshimitsu Takaoka, Michelle M. Estrella, Yu Horiuchi et al.
ESC Heart Failure
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Kidney tubule injury is associated with sodium avidity and diuretic responsiveness in acute heart failure

N. Wettersten, Yoshimitsu Takaoka, Michelle M. Estrella, Yu Horiuchi, Patrick T Murray, Joachim H Ix, Stephen Duff, Dirk J van Veldhuisen, Michael G Shlipak
article en

Abstract

Kidney tubular injury, as assessed by urine KIM-1 and NAG, is associated with greater sodium avidity and higher KIM-1 is associated with impaired diuretic responsiveness in AHF.

ESC Heart Failure
University College Dublin (IE), San Francisco VA Medical Center (US), University Medical Center Groningen (NL), University of Groningen (NL), University of California San Diego (US), VA San Diego Healthcare System (US), Mitsui Memorial Hospital (JP), San Francisco VA Health Care System (US)
Good health and well-being
Openalex Percentile: Top 31%
Acute Kidney Injury Research
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