New insights into enlarged parietal foramina: an anatomical, radiological, and histological study
Our findings support the theory that EPF represents a localized congenital ossification defect of the parietal bone rather than a pathologic erosion. Their developmental origin likely reflects aberrant parietal notch closure and persistent falcine venous structures. Understanding their embryologic and genetic basis enhances clinical recognition, guides genetic counseling, and informs surgical management strategies.
Authors
- Laurel Seltzer
- David Ezra (ORCID: https://orcid.org/0000-0001-8788-3376)
- Joseph Lockwood (ORCID: https://orcid.org/0000-0002-5289-7011)
- Noritaka Komune (ORCID: https://orcid.org/0000-0002-9521-9878)
- Joe IWANAGA
- Zachary S Weisberg
- Brian Hines
- Aaron S. Dumont
- R. Shane Tubbs
- Hotaka Kawai
Institutions
- Kurume University (JP)
- Tulane University (US)
- Ochsner Health System (US)
- St. George's University (GD)
- Kyushu University (JP)
- Okayama University (JP)
- The University of Queensland (AU)
- Cleveland Museum of Natural History (US)
- Kurume University Medical Center (JP)
- Academic College of Tel Aviv-Yafo (IL)
Publication Details
- Journal
- Child s Nervous System
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1007/s00381-026-07197-w
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00