Late-onset combined immunodeficiency and bone marrow failure in severe autoimmune hepatitis: a case report

This case highlights the importance of screening for underlying immunodeficiency in adolescents presenting with atypical or seronegative autoimmune hepatitis. Early recognition of late-onset combined immunodeficiency and related complications, such as hepatitis-associated aplastic anemia, is crucial for timely multidisciplinary management and may significantly impact patient outcomes.