A Single Centre Study to Describe the Changes in Serum Testosterone Concentration Following Application of Testosterone Gel in Post‐Menopausal Women With Hypoactive Sexual Desire Disorder (HSSD) Already Receiving This as Part of Usual Care in Conjunc

We found considerable variation in all parameters relating to testosterone pharmacokinetics in women applying 20.25 mg testosterone gel in a 3 or 4-day regime. All women described clinical benefit prior to the study, with no reports of androgen-related side-effects. Progression to a daily licensed topical formulation of testosterone, where this is not available, would be a positive step for women's health.

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Institutions

Publication Details

Journal
Clinical Endocrinology
Published
2026-03-15
DOI
https://doi.org/10.1111/cen.70119
Primary Topic
Sexual function and dysfunction studies
Type
article
Field-Weighted Citation Impact
0.00
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article

A Single Centre Study to Describe the Changes in Serum Testosterone Concentration Following Application of Testosterone Gel in Post‐Menopausal Women With Hypoactive Sexual Desire Disorder (HSSD) Already Receiving This as Part of Usual Care in Conjunc

Mark Livingston, Joanna Borzomato, Peter Nicholas Taylor, Rupinder Kochhar et al.
Clinical Endocrinology
Sexual function and dysfunction studies
article

A Single Centre Study to Describe the Changes in Serum Testosterone Concentration Following Application of Testosterone Gel in Post‐Menopausal Women With Hypoactive Sexual Desire Disorder (HSSD) Already Receiving This as Part of Usual Care in Conjunc

Mark Livingston, Joanna Borzomato, Peter Nicholas Taylor, Rupinder Kochhar, Y. A. Illangasekera, Adrian Hugh Heald, Mathilde Mordaunt, Hassan Rehman, Anne Keen, Geoff Hackett, Nicholas Panay
article en

Abstract

We found considerable variation in all parameters relating to testosterone pharmacokinetics in women applying 20.25 mg testosterone gel in a 3 or 4-day regime. All women described clinical benefit prior to the study, with no reports of androgen-related side-effects. Progression to a daily licensed topical formulation of testosterone, where this is not available, would be a positive step for women's health.

Clinical Endocrinology
University of Peradeniya (LK), University of Wolverhampton (GB), Aston University (GB), University of Manchester (GB), Salford Royal Hospital (GB), Queen Charlotte's and Chelsea Hospital (GB), The Royal Wolverhampton NHS Trust (GB), University of Wales Institute Cardiff (SG), Sheffield Hallam University (GB)
Gender equality
Openalex Percentile: Top 30%
Sexual function and dysfunction studies
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