Shengjiang Xiexin Decoction Mitigates Irinotecan-Triggered Delayed-OnsetDiarrhea by Modulating Short-Chain Fatty Acids and the TLR4-MyD88-JNK/NF-κB Pathway
This study provides a foundation for further investigation of SXD as a complementary strategy to improve the safety of irinotecan chemotherapy.
Authors
- Dongmei Chen (ORCID: https://orcid.org/0000-0002-3456-8492)
- Chao Deng (ORCID: https://orcid.org/0000-0002-2607-5575)
- Chen Chen (ORCID: https://orcid.org/0000-0003-0000-5920)
- Q. Wang (ORCID: https://orcid.org/0009-0006-3912-0052)
- Liqun Jia
- Yu Gao
Institutions
- Beijing University of Chinese Medicine (CN)
- Peking University (CN)
- China-Japan Friendship Hospital (CN)
- Dongguan People’s Hospital (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2026-03-12
- DOI
- https://doi.org/10.2174/0113816128407172251203060247
- Primary Topic
- Cancer therapeutics and mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00