Integrated In silico and In vitro Screening of Phytoconstituents as PotentialInhibitors of New Delhi Metallo-β-lactamase-1 (NDM-1)

Bis-desmethoxycurcumin from C. longa exhibits promising inhibitory activity against NDM-1-producing E. coli, supporting its potential use in adjuvant therapy to combat antibiotic resistance.

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Publication Details

Journal
Current Pharmaceutical Biotechnology
Published
2026-03-11
DOI
https://doi.org/10.2174/0113892010419139251205144039
Primary Topic
Curcumin's Biomedical Applications
Type
article
Field-Weighted Citation Impact
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article

Integrated In silico and In vitro Screening of Phytoconstituents as PotentialInhibitors of New Delhi Metallo-β-lactamase-1 (NDM-1)

Suresh Kumar Gahlawat, Ajmer Singh Grewal, Ajay Kumar, Sapna Redhu
Current Pharmaceutical Biotechnology
Curcumin's Biomedical Applications
article

Integrated In silico and In vitro Screening of Phytoconstituents as PotentialInhibitors of New Delhi Metallo-β-lactamase-1 (NDM-1)

Suresh Kumar Gahlawat, Ajmer Singh Grewal, Ajay Kumar, Sapna Redhu
article en

Abstract

Bis-desmethoxycurcumin from C. longa exhibits promising inhibitory activity against NDM-1-producing E. coli, supporting its potential use in adjuvant therapy to combat antibiotic resistance.

Current Pharmaceutical BiotechnologyVol. 27
Chaudhary Devi Lal University (IN), Shree Guru Gobind Singh Tricentenary University (IN)
Clean water and sanitation
Openalex Percentile: Top 21%
Curcumin's Biomedical Applications
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