Exosomal ZFPL1 Identifies Neuroendocrine and Stem Cell‐Like Prostate Cancer Subtypes?

ZFPL1 is a CT- and androgen-regulated protein selectively expressed in malignant prostate cells and secreted via exosomes. Its elevated plasma levels and association with aggressive disease highlight its promise as a non-invasive biomarker for PC detection and monitoring.

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Publication Details

Journal
The Prostate
Published
2026-03-15
DOI
https://doi.org/10.1002/pros.70148
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Exosomal ZFPL1 Identifies Neuroendocrine and Stem Cell‐Like Prostate Cancer Subtypes?

Neshat Masud, Girish V. Shah, Johnmesha L. Sanders, Kenneth A. Iczkowski
The Prostate
Extracellular vesicles in disease
article

Exosomal ZFPL1 Identifies Neuroendocrine and Stem Cell‐Like Prostate Cancer Subtypes?

Neshat Masud, Girish V. Shah, Johnmesha L. Sanders, Kenneth A. Iczkowski
article en

Abstract

ZFPL1 is a CT- and androgen-regulated protein selectively expressed in malignant prostate cells and secreted via exosomes. Its elevated plasma levels and association with aggressive disease highlight its promise as a non-invasive biomarker for PC detection and monitoring.

The Prostate
University of Louisiana at Monroe (US), University of California, Davis (US)
Openalex Percentile: Top 21%
Extracellular vesicles in disease
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