Mendelian Randomization Analyses Indicate a Causal Association Between Sodium-Glucose Cotransporter-1 Inhibition and Mitochondrial Function

We determined for the first time that genetically predicated SGLT1 inhibition is causally linked to a variety of mitochondrial biology processes in the European population.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2026-03-13
DOI
https://doi.org/10.2174/0109298673435453260108061203
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Mendelian Randomization Analyses Indicate a Causal Association Between Sodium-Glucose Cotransporter-1 Inhibition and Mitochondrial Function

Zi-Han Qu, Gang Fan
Current Medicinal Chemistry
Diabetes Treatment and Management
article

Mendelian Randomization Analyses Indicate a Causal Association Between Sodium-Glucose Cotransporter-1 Inhibition and Mitochondrial Function

Zi-Han Qu, Gang Fan
article en

Abstract

We determined for the first time that genetically predicated SGLT1 inhibition is causally linked to a variety of mitochondrial biology processes in the European population.

Current Medicinal ChemistryVol. 33
Xian Yang Central Hospital (CN), Shaanxi University of Chinese Medicine (CN)
Openalex Percentile: Top 23%
Diabetes Treatment and Management
DOISourceOpenAlex
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Mendelian Randomization Analyses Indicate a Causal Association Between Sodium-Glucose Cotransporter-1 Inhibition and Mitochondrial Function — Zi-Han Qu, Gang Fan · Current Medicinal Chemistry (2026) | TGRS Research Map | TGRS