Syphilitic Osteitis of the Manubrium Sterni Mimicking Malignancy: An Emerging Diagnostic Pitfall in Young Adult

Syphilitic osteitis is a rare manifestation of syphilis that occurs in < 1% of untreated cases, typically affecting the skull, tibia, and sternoclavicular region, and often mimicking malignancy. A 24-year-old man presented with 2 weeks of progressive anterior chest pain and night sweats.

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Publication Details

Journal
The Journal of Rheumatology
Published
2026-03-15
DOI
https://doi.org/10.3899/jrheum.2025-1284
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Syphilitic Osteitis of the Manubrium Sterni Mimicking Malignancy: An Emerging Diagnostic Pitfall in Young Adult

Muhammad Shahnawaz Soyfoo, Sara Kamel Rey, Xavier Cabrol
The Journal of Rheumatology
Syphilis Diagnosis and Treatment
article

Syphilitic Osteitis of the Manubrium Sterni Mimicking Malignancy: An Emerging Diagnostic Pitfall in Young Adult

Muhammad Shahnawaz Soyfoo, Sara Kamel Rey, Xavier Cabrol
article en

Abstract

Syphilitic osteitis is a rare manifestation of syphilis that occurs in < 1% of untreated cases, typically affecting the skull, tibia, and sternoclavicular region, and often mimicking malignancy. A 24-year-old man presented with 2 weeks of progressive anterior chest pain and night sweats.

The Journal of Rheumatology
Université Libre de Bruxelles (BE)
Openalex Percentile: Top 21%
Syphilis Diagnosis and Treatment
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