Molecular Insights into the MdtABC Efflux Pump Genes in Clinical Salmonella typhi Isolates from Typhoid Patients

This study highlights the alarming rise of multidrug resistance in S. typhi isolates and identifies key genetic mutations that may influence efflux pump function, potentially contributing to enhanced antibiotic resistance.

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Publication Details

Journal
Current Pharmaceutical Design
Published
2026-03-13
DOI
https://doi.org/10.2174/0113816128426430251208153115
Primary Topic
Salmonella and Campylobacter epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Molecular Insights into the MdtABC Efflux Pump Genes in Clinical Salmonella typhi Isolates from Typhoid Patients

Ibrar Khan, Sajid Ali, Sadiq Azam, Arfan Ahmad et al.
Current Pharmaceutical Design
Salmonella and Campylobacter epidemiology
article

Molecular Insights into the MdtABC Efflux Pump Genes in Clinical Salmonella typhi Isolates from Typhoid Patients

Ibrar Khan, Sajid Ali, Sadiq Azam, Arfan Ahmad, Alaa S. Alhegaili, Fazal U Samad, Noor Rehman, Muhammad .
article en

Abstract

This study highlights the alarming rise of multidrug resistance in S. typhi isolates and identifies key genetic mutations that may influence efflux pump function, potentially contributing to enhanced antibiotic resistance.

Current Pharmaceutical DesignVol. 32
Prince Sattam Bin Abdulaziz University (SA), Abdul Wali Khan University Mardan (PK), Khyber Teaching Hospital (PK), University of Peshawar (PK), University of Swabi (PK), Yeungnam University (KR)
Openalex Percentile: Top 20%
Salmonella and Campylobacter epidemiology
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