Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro‐inflammatory cytokines

Use of epidural analgesia during labour was not found to be independently associated with adverse child behavioural outcomes. Variations in maternal cytokine profiles among those choosing labour epidural analgesia or not may influence susceptibility to early behavioural differences. Replication in larger cohorts and further exploration of additional immune biomarker dynamics during pregnancy are warranted.

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Publication Details

Journal
Anaesthesia
Published
2026-03-15
DOI
https://doi.org/10.1111/anae.70203
Primary Topic
Maternal Mental Health During Pregnancy and Postpartum
Type
article
Field-Weighted Citation Impact
0.00
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article

Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro‐inflammatory cytokines

Martin F. Bjurström, Richard White, Miklós Lipcsey, Birgitta Birgisdottir et al.
Anaesthesia
Maternal Mental Health During Pregnancy and Postpartum
article

Labour epidural analgesia and early childhood behavioural outcomes: the moderating role of maternal mental health and pro‐inflammatory cytokines

Martin F. Bjurström, Richard White, Miklós Lipcsey, Birgitta Birgisdottir, Sana Asif, Hsing‐Fen Tu, Alkistis Skalkidou
article en

Abstract

Use of epidural analgesia during labour was not found to be independently associated with adverse child behavioural outcomes. Variations in maternal cytokine profiles among those choosing labour epidural analgesia or not may influence susceptibility to early behavioural differences. Replication in larger cohorts and further exploration of additional immune biomarker dynamics during pregnancy are warranted.

Anaesthesia
Uppsala University (SE), Uppsala University Hospital (SE), Umeå University (SE)
Openalex Percentile: Top 25%
Maternal Mental Health During Pregnancy and Postpartum
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