Body composition, hormonal and metabolic profiles in polycystic ovary syndrome with and without insulin resistance

Aims: This study aimed to compare body compositions, as assessed by bioelectrical impedance analysis (BIA), hormonal parameters, and metabolic profiles of women with polycystic ovary syndrome (PCOS) according to their IR status.Methods: Ninety-four women diagnosed with PCOS according to the Rotterdam criteria were included. IR was assessed in 86 patients and defined as HOMA-IR >2.5. Participants were classified as insulin-resistant (IR+) or insulin-sensitive (IR–). Anthropometric measurements, body composition parameters, oral glucose tolerance test results, lipid profiles, and hormonal parameters were compared.Results: IR was present in 51 patients, while 35 were IR–. Compared with the IR–, IR+ patients had significantly higher body weight, BMI, waist and hip circumferences, body fat percentage, fat mass, fat-free mass, muscle mass, bone mass, total body water, basal metabolic rate, metabolic age, and visceral fat ratio (p