How I Met Your Monomer: Oligomer counting for FLImP using RJMCMC

Determining the distribution of protein oligomers in a sample is crucial to understanding a wide range of biological processes. Fluorescence Localisation Imaging with Photobleaching (FLImP) is a super-resolution imaging technique used for high-precision molecular localisation in protein oligomers, however it does not currently extract oligomer state distributions. FLImP traces are repurposed here for oligomer counting with Reversible Jump MCMC (RJMCMC), providing a richer characterisation of their distributions.