Association between type 2 diabetes and site‐specific fracture risk: A systematic review and meta‐analysis of cohort studies including over 13 million participants

T2D is associated with an increased risk of fractures, especially in lower limbs (hip, ankle and foot). These findings highlight the importance of targeted fracture prevention strategies and site-specific risk assessment for individuals with T2D. However, due to the heterogeneity among studies, caution is required in the interpretation of these findings.

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Publication Details

Journal
Diabetic Medicine
Published
2026-03-13
DOI
https://doi.org/10.1111/dme.70276
Primary Topic
Bone health and osteoporosis research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between type 2 diabetes and site‐specific fracture risk: A systematic review and meta‐analysis of cohort studies including over 13 million participants

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Diabetic Medicine
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Association between type 2 diabetes and site‐specific fracture risk: A systematic review and meta‐analysis of cohort studies including over 13 million participants

Monica Kundu, Noushin Fahimfar, Sara Naderpour, Malihe Khoramdad, Clare L. Gillies, Safoora Gharibzadeh, Sonia Khavere, Paul O'Riordan, Kamlesh Khunti, Zahra Karimi
article en

Abstract

T2D is associated with an increased risk of fractures, especially in lower limbs (hip, ankle and foot). These findings highlight the importance of targeted fracture prevention strategies and site-specific risk assessment for individuals with T2D. However, due to the heterogeneity among studies, caution is required in the interpretation of these findings.

Diabetic Medicine
University of Leicester (GB), Iran University of Medical Sciences (IR), Leicester General Hospital (GB), Glenfield Hospital (GB), University of Social Welfare and Rehabilitation Sciences (IR), NIHR Leicester Biomedical Research Centre (GB), Tehran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 22%
Bone health and osteoporosis research
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