Long‐term safety of early discontinuation of antiseizure medication after resolution of acute provoked neonatal seizures
Prolonged administration of ASM for several months after resolution of acute provoked neonatal seizures may expose infants to unnecessary medications. These results provide additional evidence for safety of discontinuing ASM for most neonates soon after the resolution of acute provoked seizures-a practice that is recommended in the International League Against Epilepsy (ILAE) guideline for neonatal seizure management.
Authors
- Dana Annis
- Monica E. Lemmon (ORCID: https://orcid.org/0000-0001-6253-775X)
- Tayyba Anwar (ORCID: https://orcid.org/0000-0002-1686-8352)
- Julie Sturza (ORCID: https://orcid.org/0009-0006-1486-1890)
- Charles E. McCulloch (ORCID: https://orcid.org/0000-0002-1279-6179)
- Renée A. Shellhaas (ORCID: https://orcid.org/0000-0002-3175-3908)
- Courtney J. Wusthoff (ORCID: https://orcid.org/0000-0002-1882-5567)
- Shavonne L. Massey (ORCID: https://orcid.org/0000-0002-8496-221X)
- Cameron Thomas (ORCID: https://orcid.org/0000-0003-1529-2846)
- Hannah C. Glass (ORCID: https://orcid.org/0000-0002-3879-1966)
- Linda S. Franck (ORCID: https://orcid.org/0000-0003-4291-9181)
- Catherine Chu
- Jennifer G. Larson
- Janet S. Soul
- Madison M. Berl
- Adam L. Numis
- Elizabeth E. Rogers
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Boston Children's Hospital (US)
- Kennedy Krieger Institute (US)
- Children's Hospital of Philadelphia (US)
- Children's National (US)
- Harvard University (US)
- Duke University (US)
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- University of Michigan (US)
- Massachusetts General Hospital (US)
- Michigan Medicine (US)
- UCSF Benioff Children's Hospital (US)
- University of Pennsylvania (US)
- University of California, Davis (US)
Publication Details
- Journal
- Epilepsia
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1002/epi.70192
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00