Genetic Evidence for GLP1R Agonists in Non-Ischaemic Heart Failure
This study provides genetic support for a protective association between GLP1R activation and HF, particularly ni-HFpEF, with effects beyond glycaemia. The magnitude and subtype specificity are consistent with contemporary trial evidence and support further evaluation of GLP1R agonism in cardiometabolic HFpEF.
Authors
- Sandosh Padmanabhan (ORCID: https://orcid.org/0000-0003-3869-5808)
- Nhu Ngoc Le (ORCID: https://orcid.org/0000-0002-9373-8404)
- DK Gill
Institutions
- Imperial College London (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- ESC Heart Failure
- Published
- 2026-03-12
- DOI
- https://doi.org/10.1093/eschf/xvag077
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00