Poor clinical outcomes and immunoevasive contexture in gastric cancer patients bearing p16 high phenotype
This study identified a specific triple classification staining pattern of p16<sup>INK4a</sup> expression in GC, and demonstrated that p16<sup>INK4a</sup> OE was associated with poor clinical outcomes and evasive immune contexture.
Authors
- Chao Lin (ORCID: https://orcid.org/0000-0002-2571-2181)
- Jieti Wang
- Jiejie Xu (ORCID: https://orcid.org/0000-0001-7431-9063)
- Zhen Ling (ORCID: https://orcid.org/0009-0006-3928-687X)
- Hongyong He
- Yun Gu
- Fei Shao
- Hao Liu
- Ziqiu Zhang
- Ruochen Li
Institutions
- Shanghai Medical College of Fudan University (CN)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Shanghai Chest Hospital (CN)
- Fudan University Shanghai Cancer Center (CN)
- Zhongshan Hospital (CN)
- Shanghai Sixth People's Hospital (CN)
Publication Details
- Journal
- Cancer
- Published
- 2026-03-14
- DOI
- https://doi.org/10.1002/cncr.70363
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00