GFAP/UCH-L1 Assay for mTBI: Preanalytical Factors and Levels in Healthy Individuals—A Study on Danish Adults

The analytical precision and storage conditions of GFAP/UCH-L1 were satisfactory. Serum and plasma can be used for measurement of GFAP, whereas UCH-L1 measurement in plasma is not advised until further evaluations are conducted. The manufacturer's upper reference limits may not be suitable for our population. Thorough research on cutoff values is necessary.

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Publication Details

Journal
The Journal of Applied Laboratory Medicine
Published
2026-02-09
DOI
https://doi.org/10.1093/jalm/jfag021
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
0.00
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article

GFAP/UCH-L1 Assay for mTBI: Preanalytical Factors and Levels in Healthy Individuals—A Study on Danish Adults

Lene Rosenberg, Maj-Britt Fruekilde, Anne Lindegaard Christiansen, Ida Boegh Andersen
The Journal of Applied Laboratory Medicine
Chronic Kidney Disease and Diabetes
article

GFAP/UCH-L1 Assay for mTBI: Preanalytical Factors and Levels in Healthy Individuals—A Study on Danish Adults

Lene Rosenberg, Maj-Britt Fruekilde, Anne Lindegaard Christiansen, Ida Boegh Andersen
article en

Abstract

The analytical precision and storage conditions of GFAP/UCH-L1 were satisfactory. Serum and plasma can be used for measurement of GFAP, whereas UCH-L1 measurement in plasma is not advised until further evaluations are conducted. The manufacturer's upper reference limits may not be suitable for our population. Thorough research on cutoff values is necessary.

The Journal of Applied Laboratory Medicine
Region of Southern Denmark (DK), Hospital South West Jutland (DK)
Openalex Percentile: Top 31%
Chronic Kidney Disease and Diabetes
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