Management of early-onset knee osteoarthritis in athletes: current concepts

Abstract Early-onset knee osteoarthritis (OA) is no longer a condition of ageing joints; it is now an emerging threat to the careers of athletes in their prime. High-impact sports, repetitive microtrauma, and incomplete recovery after injury contribute to a biologically active and mechanically unstable joint environment, often years before radiographic changes appear. In this narrative review, we explore how modern sports medicine is shifting from reactive to proactive strategies, focusing on joint preservation, functional optimisation, and long-term performance sustainability. From precision diagnosis using advanced imaging and biomarkers to tailored exercise programmes, biologic injections, and targeted surgical options, the management of early-onset knee OA demands an integrated, sport-specific approach. The athlete’s return to sport is not merely a clinical milestone but a biomechanical, psychological, and strategic decision. Despite growing awareness, current guidelines fail to address the complexity of early-onset OA in high-performing individuals, and robust long-term data are lacking. This review provides an evidence-based framework to delay degeneration, empower athletes, and keep performance at the centre of care.

Authors

Institutions

Publication Details

Journal
European journal of medical research
Published
2026-03-14
DOI
https://doi.org/10.1186/s40001-026-04072-x
Primary Topic
Knee injuries and reconstruction techniques
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Management of early-onset knee osteoarthritis in athletes: current concepts

Michael Kurt Memminger, Fabrizio Rivera, Francesco Simeone, Luise Schäfer et al.
European journal of medical research
Knee injuries and reconstruction techniques
article

Management of early-onset knee osteoarthritis in athletes: current concepts

Michael Kurt Memminger, Fabrizio Rivera, Francesco Simeone, Luise Schäfer, Francesco Oliva, Filippo Migliorini, Nicola Maffulli
article en

Abstract

Abstract Early-onset knee osteoarthritis (OA) is no longer a condition of ageing joints; it is now an emerging threat to the careers of athletes in their prime. High-impact sports, repetitive microtrauma, and incomplete recovery after injury contribute to a biologically active and mechanically unstable joint environment, often years before radiographic changes appear. In this narrative review, we explore how modern sports medicine is shifting from reactive to proactive strategies, focusing on joint preservation, functional optimisation, and long-term performance sustainability. From precision diagnosis using advanced imaging and biomarkers to tailored exercise programmes, biologic injections, and targeted surgical options, the management of early-onset knee OA demands an integrated, sport-specific approach. The athlete’s return to sport is not merely a clinical milestone but a biomechanical, psychological, and strategic decision. Despite growing awareness, current guidelines fail to address the complexity of early-onset OA in high-performing individuals, and robust long-term data are lacking. This review provides an evidence-based framework to delay degeneration, empower athletes, and keep performance at the centre of care.

European journal of medical research
Queen Mary University of London (GB), Mile End Hospital (GB), Ospedale di Bolzano (IT), Ospedale SS. Annunziata (IT), Link Campus University (IT), Keele University (GB), Martin Luther University Halle-Wittenberg (DE), Sapienza University of Rome (IT), Immersion (United States) (US)
Openalex Percentile: Top 22%
Knee injuries and reconstruction techniques
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.