Comparison of proprietary and fine-tuned large language models for multi-label classification of billing codes from radiology reports

Question LLMs with high parameters possess medical knowledge, but how effective are they at predicting billing codes from radiology reports compared to smaller, fine-tuned models? Finidngs A fine-tuned ensemble model achieved competitive results and can outperform larger, proprietary LLMs. Clinical relevance Smaller, fine-tuned models offer an efficient alternative to proprietary LLMs in generating billing codes and can be integrated to assist clinical coding. This technology has the potential to transform clinical billing procedures, but its use should be overseen by qualified professional personnel.

Authors

Institutions

Publication Details

Journal
European Radiology
Published
2026-03-14
DOI
https://doi.org/10.1007/s00330-026-12445-3
Primary Topic
Topic Modeling
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Comparison of proprietary and fine-tuned large language models for multi-label classification of billing codes from radiology reports

René Hosch, Johannes Haubold, Eva Maria Hartmann, Cynthia Sabrina Schmidt et al.
European Radiology
Topic Modeling
article

Comparison of proprietary and fine-tuned large language models for multi-label classification of billing codes from radiology reports

René Hosch, Johannes Haubold, Eva Maria Hartmann, Cynthia Sabrina Schmidt, Lale Umutlu, Michael Forsting, Katarzyna Borys, Ahmad Idrissi-Yaghir, Kamyar Arzideh, Sina Warmer, Bahadir Eryilmaz, Felix Nensa, Henning Schäfer
article en

Abstract

Question LLMs with high parameters possess medical knowledge, but how effective are they at predicting billing codes from radiology reports compared to smaller, fine-tuned models? Finidngs A fine-tuned ensemble model achieved competitive results and can outperform larger, proprietary LLMs. Clinical relevance Smaller, fine-tuned models offer an efficient alternative to proprietary LLMs in generating billing codes and can be integrated to assist clinical coding. This technology has the potential to transform clinical billing procedures, but its use should be overseen by qualified professional personnel.

European Radiology
Ruhrlandklinik (DE), Essen University Hospital (DE)
Peace, Justice and strong institutions
Openalex Percentile: Top 25%
Topic Modeling
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.