NEFL is associated with inhibition of odontoblastic process in odontohypophosphatasia
Enhanced expression of NEFL in Odonto-OD-like cells negatively correlates with OD morphology and may be relevant to odontoblast morphological abnormalities associated with odontohypophosphatasia; however, generalization to other odonto-HPP genotypes requires additional patient-derived lines.
Authors
- Yasuhisa Ohata (ORCID: https://orcid.org/0000-0001-6084-6620)
- Mikihiko Kogo (ORCID: https://orcid.org/0000-0002-4556-2491)
- Toshihiko Nambara (ORCID: https://orcid.org/0009-0001-3107-0680)
- Takeshi Taketani (ORCID: https://orcid.org/0000-0002-3257-1305)
- Yasuji Kitabatake (ORCID: https://orcid.org/0000-0002-2907-9512)
- Akira Nozoe (ORCID: https://orcid.org/0000-0002-2674-2980)
- Chiho Nakano
- Susumu Tanaka (ORCID: https://orcid.org/0000-0003-4804-7839)
- Kazuaki Miyagawa (ORCID: https://orcid.org/0000-0003-4014-1847)
- Kenichi Yamamoto
- T. Kubota
- Keiichi Ozono
- Makoto Fujiwara
Institutions
- Shimane University (JP)
- Osaka City University (JP)
- Osaka Health Science University (JP)
- Osaka Hospital (JP)
- Osaka Dental University (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Journal of Bone and Mineral Metabolism
- Published
- 2026-03-14
- DOI
- https://doi.org/10.1007/s00774-026-01703-5
- Primary Topic
- Alkaline Phosphatase Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science