Metabolomics reveals early pregnancy serum metabolic changes and predictive biomarkers in gestational diabetes mellitus

This study identified significant serum metabolic changes during early pregnancy in GDM women, unveiling potential mechanisms underlying the early development of GDM and prognostic biomarkers. These findings not only deepen our understanding of metabolic disturbances in GDM but also provide crucial theoretical foundations for early screening and precision interventions in clinical practice.

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Publication Details

Journal
Nutrition & Metabolism
Published
2026-03-14
DOI
https://doi.org/10.1186/s12986-026-01107-2
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Metabolomics reveals early pregnancy serum metabolic changes and predictive biomarkers in gestational diabetes mellitus

Juan Dai, Ya Yuan, Xiaodie LI, Xue Gao et al.
Nutrition & Metabolism
Gestational Diabetes Research and Management
article

Metabolomics reveals early pregnancy serum metabolic changes and predictive biomarkers in gestational diabetes mellitus

Juan Dai, Ya Yuan, Xiaodie LI, Xue Gao, Xuemei Guo, Feng Wang, Jingzhong Ou, Chuchu Zhao, Jinping Liang, Ting Zhang
article en

Abstract

This study identified significant serum metabolic changes during early pregnancy in GDM women, unveiling potential mechanisms underlying the early development of GDM and prognostic biomarkers. These findings not only deepen our understanding of metabolic disturbances in GDM but also provide crucial theoretical foundations for early screening and precision interventions in clinical practice.

Nutrition & Metabolism
Chengdu Medical College (CN), Third People's Hospital of Chengdu (CN), Chengdu Second People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 20%
Gestational Diabetes Research and Management
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