Determining the Minimal Clinically Important Difference of the 40‐Item Smell Identification Test in People With Cystic Fibrosis

This CF-specific SIT threshold provides a clinically interpretable cut-off for assessing olfaction. These findings establish a foundation for future work and highlight the importance of developing disease-specific MCIDs to guide clinical care and research.

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Publication Details

Journal
International Forum of Allergy & Rhinology
Published
2026-03-13
DOI
https://doi.org/10.1002/alr.70136
Primary Topic
Olfactory and Sensory Function Studies
Type
article
Field-Weighted Citation Impact
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article

Determining the Minimal Clinically Important Difference of the 40‐Item Smell Identification Test in People With Cystic Fibrosis

Anna C. Zemke, Amanda L. Stapleton, Jennifer L. Taylor‐Cousar, Timothy L. Smith et al.
International Forum of Allergy & Rhinology
Olfactory and Sensory Function Studies
article

Determining the Minimal Clinically Important Difference of the 40‐Item Smell Identification Test in People With Cystic Fibrosis

Anna C. Zemke, Amanda L. Stapleton, Jennifer L. Taylor‐Cousar, Timothy L. Smith, D. Li, Jeffrey D. Suh, Jeremiah A. Alt, Rodney J. Schlosser, M. Strand, Ashoke R. Khanwalkar, David Baraghoshi, Patricia H. Eshaghian, Naweed I. Chowdhury, Jayakar V. Nayak, Todd Bodner, D. Beswick, David A. Gudis, Marilene B. Wang, Jess Collin Mace, Grant A. Turner, Zachary M. Soler, Michelle J. Lee, Eugene Oh, Anne E. Getz, Jessa E Miller, Michael Chang, Jennifer L. Goralski, Milene T. Saavedra, Zara Patel, Brent Senior, Adam J. Kimple, Jivianne T. Lee, Jonathan B. Overdevest, Peter H. Hwang, Daniella K. Safatian
article en

Abstract

This CF-specific SIT threshold provides a clinically interpretable cut-off for assessing olfaction. These findings establish a foundation for future work and highlight the importance of developing disease-specific MCIDs to guide clinical care and research.

International Forum of Allergy & Rhinology
University of North Carolina at Chapel Hill (US), Portland State University (US), Medical University of South Carolina (US), University of California, Los Angeles (US), Oregon Health & Science University (US), University of Pittsburgh (US), University of Utah (US), University of Michigan (US), National Jewish Health (US), Michigan Medicine (US), Stanford Medicine (US), Columbia University (US), Vanderbilt University Medical Center (US), University of Colorado Denver (US)
Openalex Percentile: Top 20%
Olfactory and Sensory Function Studies
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