Key challenges in traumatic brain injury treatment: integrated mechanisms, translational animal models, and advanced drug delivery systems

<b>Conclusion:</b> Links secondary injury mechanisms with rationally designed DDS may improve translation outcomes. Enhancing preclinical riogr and aligning formulation strategies with pathophysiological targets are critical for developmenting effective TBI therapies.

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Publication Details

Journal
International Journal of Neuroscience
Published
2026-03-14
DOI
https://doi.org/10.1080/00207454.2026.2644509
Primary Topic
Traumatic Brain Injury and Neurovascular Disturbances
Type
article
Field-Weighted Citation Impact
0.00
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article

Key challenges in traumatic brain injury treatment: integrated mechanisms, translational animal models, and advanced drug delivery systems

Junzhe Yang, Jingzhe Wang, Yu Zhang, Shan Ma
International Journal of Neuroscience
Traumatic Brain Injury and Neurovascular Disturbances
article

Key challenges in traumatic brain injury treatment: integrated mechanisms, translational animal models, and advanced drug delivery systems

Junzhe Yang, Jingzhe Wang, Yu Zhang, Shan Ma
article en

Abstract

<b>Conclusion:</b> Links secondary injury mechanisms with rationally designed DDS may improve translation outcomes. Enhancing preclinical riogr and aligning formulation strategies with pathophysiological targets are critical for developmenting effective TBI therapies.

International Journal of Neuroscience
Shandong University of Traditional Chinese Medicine (CN), Beijing Radiation Center (CN)
Good health and well-being
Openalex Percentile: Top 29%
Traumatic Brain Injury and Neurovascular Disturbances
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