Antiproliferative activity, phytochemistry, network pharmacology, molecular docking and gene expression analysis of Maerua edulis extracts against human cervical cancer cell line
The results of our study suggest the potential therapeutic benefits of M. edulis in the treatment and management of cervical cancer. Further in-vivo studies are recommended to validate these findings and establish their safety profile.
Authors
- Sally Wambui Kamau (ORCID: https://orcid.org/0009-0006-8786-1103)
- Dorothy Wavinya Nyamai (ORCID: https://orcid.org/0000-0003-4704-9883)
- James Kuria
- Sospeter Ngoci Njeru (ORCID: https://orcid.org/0000-0003-1154-0777)
- Fredrick Mutie Musila (ORCID: https://orcid.org/0000-0002-6219-8150)
- Inyani John Lino Lagu (ORCID: https://orcid.org/0009-0006-0543-4694)
- Rakita Letoluo
- Vyacheslav Kungurtsev
Institutions
- Technical University of Kenya (KE)
- University of Juba (SS)
- Manchester Academic Health Science Centre (GB)
- University of Manchester (GB)
- Kenya Medical Research Institute (KE)
- African Centre for Technology Studies (KE)
- Czech Technical University in Prague (CZ)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2026-03-14
- DOI
- https://doi.org/10.1186/s12906-026-05321-6
- Primary Topic
- Tannin, Tannase and Anticancer Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00