Associations of cumulative exposure and dynamic trajectories of cholesterol-HDL-glucose (CHG) index with cardiovascular disease in middle-aged and older Chinese adults: a longitudinal analysis
Our research indicates that both cuCHG and CHG changes are associated with CVD risk in middle-aged and older adults, particularly for those with consistently high-risk CHG levels, which are linked to a significantly increased CVD risk. In clinical practice, monitoring long-term CHG changes and maintaining relatively stable levels may help prevent CVD in this population.
Authors
- Qiyuan Lyu (ORCID: https://orcid.org/0000-0001-8866-3578)
- Bei Liu (ORCID: https://orcid.org/0000-0003-4331-2138)
- Yuting Zhang (ORCID: https://orcid.org/0000-0002-5683-7286)
- Yaofei Xie
- Yanling Du
- Peng Xiong
- Yuan Zhu
Institutions
- Nanjing University of Chinese Medicine (CN)
- Jinan University (CN)
- Shenzhen University (CN)
- Air Force Engineering University (CN)
- Wuhan No.1 Hospital (CN)
- Wuhan No. 7 Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2026-03-15
- DOI
- https://doi.org/10.1186/s12933-026-03137-9
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00