Antidiabetic effects of <i>Gymnema sylvestre</i> and metformin co-therapy in a type 2 diabetic rat model

This study demonstrated that metformin and GS, individually and in combination, improved glycemic control and metabolic outcomes in T2DM rats. While metformin showed the greater efficacy, combination therapy provided additive benefits, supporting GS as a potential adjunct in T2DM management.

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Publication Details

Journal
World Journal of Experimental Medicine
Published
2026-03-14
DOI
https://doi.org/10.5493/wjem.v16.i1.116252
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Antidiabetic effects of Gymnema sylvestre and metformin co-therapy in a type 2 diabetic rat model

Megh Singh Dhakad, Niket Rai, Mirza Masroor Ali Beg, Vandana Roy et al.
World Journal of Experimental Medicine
Natural Antidiabetic Agents Studies
article

Antidiabetic effects of Gymnema sylvestre and metformin co-therapy in a type 2 diabetic rat model

Megh Singh Dhakad, Niket Rai, Mirza Masroor Ali Beg, Vandana Roy, Akhilesh Mishra, Ajay Kodiyatar
article en

Abstract

This study demonstrated that metformin and GS, individually and in combination, improved glycemic control and metabolic outcomes in T2DM rats. While metformin showed the greater efficacy, combination therapy provided additive benefits, supporting GS as a potential adjunct in T2DM management.

World Journal of Experimental MedicineVol. 16(1)
Ala-Too International University (KG), Maulana Azad Medical College (IN), Chirayu Medical College & Hospital (IN)
Good health and well-being
Openalex Percentile: Top 23%
Natural Antidiabetic Agents Studies
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