Trajectories of quality of life, anxiety and depressive symptomatology, and health‐related work productivity after first seizure events
This study investigated changes in quality of life, anxiety and depressive symptomatology, and health-related work productivity over a 12-month period for adults with first seizure events. Participants reported improvements in quality of life, reduced sick days, increased productivity at work, and less need for informal care. Concerningly, there was no change in their anxiety and depressive symptoms. The findings of this study may prompt first seizure clinicians to regularly screen patients for anxiety and depressive disorders, and treat these appropriately.
Authors
- Danny Liew (ORCID: https://orcid.org/0000-0002-0131-623X)
- Jacob Pellinen (ORCID: https://orcid.org/0000-0002-0747-7210)
- Hue Mun Au Yong (ORCID: https://orcid.org/0000-0001-9420-0641)
- Alison Conquest (ORCID: https://orcid.org/0009-0000-9388-1342)
- John‐Paul Nicolo (ORCID: https://orcid.org/0000-0002-0473-6475)
- P. W. K. Kwan
- Wendyl D’Souza
- Terence J. O’Brien
- Chris Tailby
- Zhibin Chen
- Zanfina Ademi
- David N. Vaughan
- Emma Foster
- Patrick W. Carney
Institutions
- The Royal Melbourne Hospital (AU)
- The University of Melbourne (AU)
- Florey Institute of Neuroscience and Mental Health (AU)
- St Vincent's Hospital Melbourne (AU)
- Eastern Health (AU)
- Alfred Health (AU)
- Austin Health (AU)
- Monash University (AU)
- University of Colorado Denver (US)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2026-03-14
- DOI
- https://doi.org/10.1002/epi4.70249
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00