Cross-Trait Genome-Wide Association Studies Identify Shared Genetic Risk Loci Between Psoriasis and Metabolic Syndrome and Their Associated Traits

Shared genetic loci, pleiotropic genes, and core biological pathways between PsO and multiple MetS-related traits were identified, and potential intervention targets were highlighted, providing genetic evidence to support subsequent functional investigations.

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Publication Details

Journal
Metabolic Syndrome and Related Disorders
Published
2026-03-14
DOI
https://doi.org/10.1177/15578518261426293
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

Cross-Trait Genome-Wide Association Studies Identify Shared Genetic Risk Loci Between Psoriasis and Metabolic Syndrome and Their Associated Traits

D. Y. Wang, Wanchun Wang, Ping Zhou, Xin Jiang et al.
Metabolic Syndrome and Related Disorders
Psoriasis: Treatment and Pathogenesis
article

Cross-Trait Genome-Wide Association Studies Identify Shared Genetic Risk Loci Between Psoriasis and Metabolic Syndrome and Their Associated Traits

D. Y. Wang, Wanchun Wang, Ping Zhou, Xin Jiang, Qi Zhang
article en

Abstract

Shared genetic loci, pleiotropic genes, and core biological pathways between PsO and multiple MetS-related traits were identified, and potential intervention targets were highlighted, providing genetic evidence to support subsequent functional investigations.

Metabolic Syndrome and Related Disorders
Jiangxi University of Traditional Chinese Medicine (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 21%
Psoriasis: Treatment and Pathogenesis
DOISourceOpenAlex
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