Urinary Albumin-to-Creatinine Associates More Closely than Protein-to-Creatinine Ratio with Kidney Outcomes in Pediatric Chronic Kidney Disease
Both uACR and uPCR were independently associated with CKD progression in this pediatirc cohort. In direct comparison, uACR demonstrated stronger associations with adverse kidney outcomes, suggesting a comparatively greater prognostic signal and supporting current guideline emphasis on albuminuria for risk stratification and intervention outcome monitoring.
Authors
- Julia Thumfart (ORCID: https://orcid.org/0000-0003-1162-5295)
- Francesca Lugani (ORCID: https://orcid.org/0000-0002-4189-8561)
- Jonas Hofstetter (ORCID: https://orcid.org/0000-0001-6328-9575)
- F. Schaefer
- Ali Düzova (ORCID: https://orcid.org/0000-0002-4365-2995)
- Sheila Murunga
- Lukasz Obrycki
- Aysun K Bayazit
- Justine Bacchetta
- Anke Doyon
- Uwe Querfeld
- Jerome Harambat
- Rukshana Shroff
- Anette Melk
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Université de Bordeaux (FR)
- Heidelberg University (DE)
- Great Ormond Street Hospital (GB)
- Istituto Giannina Gaslini (IT)
- University Hospital Heidelberg (DE)
- Medizinische Hochschule Hannover (DE)
- Hôpital Femme Mère Enfant (FR)
- Hospices Civils de Lyon (FR)
- Bordeaux Population Health (FR)
- Children's Memorial Health Institute (PL)
- University College London (GB)
- Cukurova University (TR)
- Hacettepe University (TR)
- Charité - Universitätsmedizin Berlin (DE)
- Heidelberg University (US)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1093/ndt/gfag061
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00