Between-centre variation in antibiotic therapeutic drug monitoring and obtaining surveillance cultures in Dutch ICUs: A retrospective observational study
Substantial variation was observed between ICUs, indicating room for quality improvement. This could not be explained by case-mix, which suggests that organizational factors are possible drivers of this variation.
Authors
- Joanna E. Klopotowska (ORCID: https://orcid.org/0000-0002-9707-5740)
- Martijn van Tellingen
- Nicolette F. de Keizer (ORCID: https://orcid.org/0000-0002-6651-1730)
- Corstiaan A. den Uil (ORCID: https://orcid.org/0000-0003-0635-2843)
- Nicole P.E. Deetman
- Tom Dormans (ORCID: https://orcid.org/0000-0002-6169-7839)
- Nuray Kuşadasi (ORCID: https://orcid.org/0000-0003-3504-0996)
- Marie-José Roos-Blom (ORCID: https://orcid.org/0000-0003-4066-607X)
- Daphne Stegink (ORCID: https://orcid.org/0009-0005-5980-0883)
- E. H. R. Van Essen
- D. A. Dongelmans
- Barbara Festen-Spanjer
- Roy van den Berg
- Lettie A.E. van den Berg
- Pamela Sneekes
- M. Sesmu Arbous
- Jeroen A. Schouten
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Albert Schweitzer Ziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- Maasstad Ziekenhuis (NL)
- Ziekenhuis Gelderse Vallei (NL)
- Zuyderland Medisch Centrum (NL)
- Haga Hospital (NL)
- Elisabeth-TweeSteden Ziekenhuis (NL)
- Amsterdam University Medical Centers (NL)
- 's Heeren Loo (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Critical Care
- Published
- 2026-03-14
- DOI
- https://doi.org/10.1016/j.jcrc.2026.155524
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 0.00