Molecular epidemiology of rotavirus causing diarrhea among under-five children after the introduction of rotavirus vaccines, Rotavac and Rotasiil, into the national immunization program of India
Rotavirus vaccination significantly reduced disease burden among under-five children in India. G3P[8] remained consistently dominant across regions, vaccine types, and years. Regional and vaccine-specific differences were evident, but trends suggest natural viral evolution may outweigh vaccine-driven selection. Sustained surveillance is essential to detect emerging strains and ensure long-term vaccine effectiveness.
Authors
- N. Nair (ORCID: https://orcid.org/0000-0002-2847-3120)
- Sidhartha Giri (ORCID: https://orcid.org/0000-0003-3927-7392)
- Namrata Kharat (ORCID: https://orcid.org/0009-0001-9347-9836)
- Shainey Alokit Khakha (ORCID: https://orcid.org/0000-0002-9831-9081)
- Varsha Sudhir Chaudhary (ORCID: https://orcid.org/0009-0007-3657-040X)
- Anupama Machathi (ORCID: https://orcid.org/0009-0008-2053-4209)
- Reddy N. Samarasimha
- Gagandeep Kang
- Tintu Varghese
- Prasanna Samuel
- Venkata Raghava Mohan
Institutions
- Christian Medical College, Vellore (IN)
- Indian Council of Medical Research (IN)
- Regional Medical Research Centre (IN)
- National Institute of Nutrition (IN)
Publication Details
- Journal
- Virology Journal
- Published
- 2026-03-14
- DOI
- https://doi.org/10.1186/s12985-026-03126-0
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00