Lower Rates of Intraocular Inflammation with Aflibercept 8 mg Delivered via Pre-Filled Syringe Versus Vial
In a real-world setting, aflibercept 8 mg was associated with a higher incidence of IOI than reported in pivotal trials, particularly when administered from vials. Conversion to the PFS markedly reduced the incidence, suggesting a formulation- or preparation-related effect. All cases were mild, anterior, and reversible under topical therapy without long-term visual impact.
Authors
- Laura Hoffmann (ORCID: https://orcid.org/0009-0008-8803-7938)
- Katja Hatz
Institutions
- University of Basel (CH)
- Vista Klinik (CH)
Publication Details
- Journal
- Ophthalmology and Therapy
- Published
- 2026-03-14
- DOI
- https://doi.org/10.1007/s40123-026-01349-6
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00