Urinary Tract Infections and Antibiotic Susceptibility Patterns in Sheki, Azerbaijan

Aim: To describe the etiologic distribution of culture-confirmed urinary tract infections (UTIs) in the Sheki region and summarize organism-specific susceptibility patterns under EUCAST interpretation. Methods: We retrospectively analyzed urine specimens processed in a single microbiology laboratory between September 2024 and April 2025. Specimens were cultured on blood agar and EMB agar and incubated aerobically at 37°C for 24–48 hours. Isolates were identified using the API system, and antimicrobial susceptibility has been determined by disk diffusion per EUCAST; duplicate and contaminated submissions were excluded. Analyses were descriptive only. Results: Significant growth was found in 42 of 85 applications (49.4%) .The mostcammon causative was Echerichia coli (20/41; 47.6%)and four strains(20%)were found to be extended-spectrum beta lactamase(ESBL)-pozitive.ESBL-pozitive aminoglycoside resistance and cefosporin resistance were observed in Klebsiella oxytoca and Klebsiella pneumaniae strains.Xinolone persistence was most common in Citrobacter spp.Aminoglycoside resistance was observed in Echerichia coli,Klebsiella spp and Raoultella spp..No antibiotic resistance was detected in Qram-positive bacteria.Conclusion: Local susceptibility data support narrow-spectrum empiric regimens for uncomplicated UTIs (notably nitrofurantoin and fosfomycin), while fluoroquinolones and broad-spectrum β-lactams should be reserved given resistance and ecological considerations. Limitations include the single-center, retrospective design, small numbers for certain taxa, and absence of adjusted analyses; larger, prospective studies are warranted.