Branched Schrödinger Bridge Matching.

Predicting the intermediate trajectories between an initial and target distribution is a central problem in generative modeling. Existing approaches, such as flow matching and Schrödinger bridge matching, effectively learn mappings between two distributions by modeling a single stochastic path. However, these methods are inherently limited to unimodal transitions and cannot capture <i>branched</i> or <i>divergent</i> evolution from a common origin to multiple distinct modes. To address this, we introduce <b>Branched Schrödinger Bridge Matching (BranchSBM)</b>, a novel framework that learns branched Schrödinger bridges. BranchSBM parameterizes multiple time-dependent velocity fields and growth processes, enabling the representation of population-level divergence into multiple terminal distributions. We show that BranchSBM is not only more expressive but also essential for tasks involving multi-path surface navigation, modeling cell fate bifurcations from homogeneous progenitor states, and simulating diverging cellular responses to perturbations.

Authors

Institutions

Publication Details

Journal
PubMed
Published
2026-03-02
Primary Topic
Generative Adversarial Networks and Image Synthesis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Branched Schrödinger Bridge Matching.

Pranam Chatterjee, Siqi Tang, Yinuo Zhang, Alexander Tong
PubMed
Generative Adversarial Networks and Image Synthesis
article

Branched Schrödinger Bridge Matching.

Pranam Chatterjee, Siqi Tang, Yinuo Zhang, Alexander Tong
article en

Abstract

Predicting the intermediate trajectories between an initial and target distribution is a central problem in generative modeling. Existing approaches, such as flow matching and Schrödinger bridge matching, effectively learn mappings between two distributions by modeling a single stochastic path. However, these methods are inherently limited to unimodal transitions and cannot capture <i>branched</i> or <i>divergent</i> evolution from a common origin to multiple distinct modes. To address this, we introduce <b>Branched Schrödinger Bridge Matching (BranchSBM)</b>, a novel framework that learns branched Schrödinger bridges. BranchSBM parameterizes multiple time-dependent velocity fields and growth processes, enabling the representation of population-level divergence into multiple terminal distributions. We show that BranchSBM is not only more expressive but also essential for tasks involving multi-path surface navigation, modeling cell fate bifurcations from homogeneous progenitor states, and simulating diverging cellular responses to perturbations.

PubMed
Duke-NUS Medical School (SG), University of Pennsylvania (US), Voith (United States) (US)
Life below water
Openalex Percentile: Top 22%
Generative Adversarial Networks and Image Synthesis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.