Dynamic expression of complement receptor immunoglobulin (CRIg) on monocytes and its role in phagocytosis and killing of Staphylococcus aureus
The data provide compelling evidence that monocytes express functional CRIg, relevant to the cells' anti-microbial role of the 'wandering' phagocyte and consolidate a view that CRIg is widely expressed in our phagocytic cell system, similar to the classical complement receptors CR3 and CR4.
Authors
- Charles S. Hii (ORCID: https://orcid.org/0000-0002-7107-8935)
- Timothy Sadlon (ORCID: https://orcid.org/0000-0002-4821-2462)
- Annabelle Small (ORCID: https://orcid.org/0000-0001-6275-2847)
- Trishni Putty (ORCID: https://orcid.org/0000-0003-1617-0381)
- Khalida Perveen (ORCID: https://orcid.org/0000-0002-1499-1736)
- Muhammad Yaaseen Gulam
- Andy Ngo
- M. Wechalekar
- Simon C. Barry (ORCID: https://orcid.org/0000-0002-0597-7609)
- Amie Patel (ORCID: https://orcid.org/0000-0002-8433-6083)
- Antonio Ferrante
- Alex Quach
- Nikki Black
- Cameron D. Skurray
- Gailin Yang
Institutions
- Singapore General Hospital (SG)
- Women's and Children's Hospital (AU)
- Flinders Medical Centre (AU)
- Women's and Children's Health Network (AU)
- National Neuroscience Institute (SG)
- The University of Adelaide (AU)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1186/s12929-025-01212-z
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Channel 7 Children's Research Foundation
- National Health and Medical Research Council