Association between anti-rituximab antibodies and treatment efficacy of rituximab in membranous nephropathy

This study confirms that adult patients with MN who are ARA positive have a higher relapse rate after initial RTX treatment. Patients who are RTX-resistant and ARA positive can achieve rapid clinical remission after receiving obinutuzumab treatment.

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2026-03-12
DOI
https://doi.org/10.1093/ndt/gfag054
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between anti-rituximab antibodies and treatment efficacy of rituximab in membranous nephropathy

Yuna Chen, Haofei Hu, Shaodong Luan, Wei Liu et al.
Nephrology Dialysis Transplantation
Renal Diseases and Glomerulopathies
article

Association between anti-rituximab antibodies and treatment efficacy of rituximab in membranous nephropathy

Yuna Chen, Haofei Hu, Shaodong Luan, Wei Liu, Rui Xue, Zigan Xu, Kang Li, Biao Huang, Ricong Xu, Zhihang Su, Di Wu, Yingbo liu, Yang Liu, Liling Wu, Qijun Wan
article en

Abstract

This study confirms that adult patients with MN who are ARA positive have a higher relapse rate after initial RTX treatment. Patients who are RTX-resistant and ARA positive can achieve rapid clinical remission after receiving obinutuzumab treatment.

Nephrology Dialysis Transplantation
Zhejiang Sci-Tech University (CN), Longgang Central Hospital (CN), Changzhou Institute of Technology (CN), First Affiliated Hospital of Jinan University (CN), Shenzhen Second People's Hospital (CN)
Zero hunger
Openalex Percentile: Top 32%
Renal Diseases and Glomerulopathies
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