Clinical phenotype and prognosis of Patients with Diabetic Kidney Disease complicated by a Primary Podocytopathy

DN with concurrent primary podocytopathy represents a distinct clinical entity characterized by nephrotic-range proteinuria, ultrastructural podocyte effacement, and favorable response to immunosuppressive therapy. Early renal biopsy incorporating FPW assessment enables targeted therapy to mitigate ESKD progression in this high-risk phenotype.

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2026-03-11
DOI
https://doi.org/10.1093/ndt/gfag050
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical phenotype and prognosis of Patients with Diabetic Kidney Disease complicated by a Primary Podocytopathy

Yue Zhou, Lei Nie, Ming-hui Zhao, Su-xia Wang et al.
Nephrology Dialysis Transplantation
Renal Diseases and Glomerulopathies
article

Clinical phenotype and prognosis of Patients with Diabetic Kidney Disease complicated by a Primary Podocytopathy

Yue Zhou, Lei Nie, Ming-hui Zhao, Su-xia Wang, Hui Wang
article en

Abstract

DN with concurrent primary podocytopathy represents a distinct clinical entity characterized by nephrotic-range proteinuria, ultrastructural podocyte effacement, and favorable response to immunosuppressive therapy. Early renal biopsy incorporating FPW assessment enables targeted therapy to mitigate ESKD progression in this high-risk phenotype.

Nephrology Dialysis Transplantation
Peking University (CN), Peking University Shenzhen Hospital (CN), Peking University First Hospital (CN), Peking University Third Hospital (CN)
Good health and well-being
Openalex Percentile: Top 32%
Renal Diseases and Glomerulopathies
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