Impact of Combined Anticoagulant and Antiplatelet Therapy in Older Patients With Atrial Fibrillation: ANAFIE Subanalysis
In older patients with atrial fibrillation, OAC+APD therapy was associated with higher incidence of cardiovascular death than OAC monotherapy, without significant differences in other clinical outcomes. For patients requiring combination therapy, DOACs may be preferable to warfarin.
Authors
- Naruhiko Kamogawa (ORCID: https://orcid.org/0000-0002-5177-8248)
- ANAFIE investigators
- Hiroaki Kobayashi
- Kaori Miwa
- Shinya Suzuki
- Takenori Yamaguchi
- Masafumi Ihara
- Kazunori Toyoda
- Sohei Yoshimura
- Takeshi Yamashita
- Hiroshi Inoue
- Manabu Inoue
- Masatoshi Koga
- Tetsuro Ago
Institutions
- Kyushu University (JP)
- Daiichi Sankyo (Germany) (DE)
- Cardiovascular Institute Hospital (JP)
- National Cerebral and Cardiovascular Center (JP)
- Daiichi-Sankyo (South Korea) (KR)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1161/jaha.125.047724
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00