IL10RB expression in cancer cells is associated with evolutionary changes to solidify treatment resistance
This study revealed that IL10RB is a key molecule in cancer intractability after achieving snail-induced EMT. Targeting IL10RB may be a promising strategy for improving clinical outcomes in the treatment of cancer.
Authors
- Hiroshi Imazeki
- Aki Takaiwa
- Masayoshi Toyoura
- Chie Kudo-Saito
- Hitomi Masuda
- Hiroki Ozawa
Institutions
- National Cancer Centre Japan (JP)
- Japan Bio Products (Japan) (JP)
- National Cancer Research Institute (GB)
Publication Details
- Journal
- BJC Reports
- Published
- 2026-03-13
- DOI
- https://doi.org/10.1038/s44276-026-00211-3
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00