Normo-phosphatemic tumoral calcinosis in a preadolescent girl- a diagnostic dilemma; a case report

Tumoral calcinosis (TC) is a rare benign disorder characterized by periarticular calcium phosphate deposition, most often affecting children and adolescents. Its rarity and resemblance to other calcified soft-tissue masses may delay diagnosis. We report a 10-year-old girl with progressively enlarging, painless periarticular masses involving both elbows and the right buttock, with functional limitation of the right elbow. Laboratory evaluation showed no major metabolic abnormality, consistent with a normophosphataemic variant. Radiographs demonstrated multilobulated extra-articular calcified soft-tissue lesions without bone erosion. The symptomatic right elbow mass was surgically excised, and histopathology confirmed tumoral calcinosis. Postoperatively, the patient achieved excellent functional recovery. TC should be considered in children presenting with painless periarticular calcified masses even in the presence of normal phosphate levels. Surgical excision is effective for symptomatic lesions, and long-term follow-up is important because recurrence may occur.

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Publication Details

Journal
Egyptian Pediatric Association Gazette
Published
2026-03-13
DOI
https://doi.org/10.1186/s43054-026-00529-0
Primary Topic
Parathyroid Disorders and Treatments
Type
article
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article

Normo-phosphatemic tumoral calcinosis in a preadolescent girl- a diagnostic dilemma; a case report

Alex Mashaka, Shindo Isack Kilawa, Mlekwa G. Mgomi, Innocent Mosha et al.
Egyptian Pediatric Association Gazette
Parathyroid Disorders and Treatments
article

Normo-phosphatemic tumoral calcinosis in a preadolescent girl- a diagnostic dilemma; a case report

Alex Mashaka, Shindo Isack Kilawa, Mlekwa G. Mgomi, Innocent Mosha, Peter Magembe Mrimba, David Antanamsu, Daudi Gervas Katwana, Mpola Tamambele, Limika Lyatuu, Godfrey Malangwa, Deogratius M. Manyama, Magdalena T. Mbeyale, Abubakar R. Hamis, Happyfania P. Shayo, Bernard Nyanza, Andrea Hondo
article en

Abstract

Tumoral calcinosis (TC) is a rare benign disorder characterized by periarticular calcium phosphate deposition, most often affecting children and adolescents. Its rarity and resemblance to other calcified soft-tissue masses may delay diagnosis. We report a 10-year-old girl with progressively enlarging, painless periarticular masses involving both elbows and the right buttock, with functional limitation of the right elbow. Laboratory evaluation showed no major metabolic abnormality, consistent with a normophosphataemic variant. Radiographs demonstrated multilobulated extra-articular calcified soft-tissue lesions without bone erosion. The symptomatic right elbow mass was surgically excised, and histopathology confirmed tumoral calcinosis. Postoperatively, the patient achieved excellent functional recovery. TC should be considered in children presenting with painless periarticular calcified masses even in the presence of normal phosphate levels. Surgical excision is effective for symptomatic lesions, and long-term follow-up is important because recurrence may occur.

Egyptian Pediatric Association GazetteVol. 74(1)
Muhimbili University of Health and Allied Sciences (TZ), Kilimanjaro Christian Medical Centre (TZ), Muhimbili National Hospital (TZ)
Openalex Percentile: Top 32%
Parathyroid Disorders and Treatments
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